- The ruins are one of the largest prehistoric structures in North America, rising from the Sonoran Desert floor near the Gila River
- The Hohokam Indians of the Gila Valley built the 14th-century structure, which is the largest known structure they built
- The name "Casa Grande" means "great house" or "big house" in Spanish
- The ruins preserve an Ancestral Sonoran Desert People's farming community and "Great House"
- From the US National Park Service: "... (in existence around) 1350 C.E. One of the largest prehistoric structures ever built in North America, its purpose remains a mystery. Archeologists have discovered evidence that the ancestral Sonoran Desert people who built the Casa Grande also developed wide-scale irrigation farming and extensive trade connections which lasted over a thousand years until about 1450 C.E. Archeologists call a site where there are earthen buildings, red on buff pottery, and extensive canals "Hohokam" but this is not the name of a tribe or a people. Years of misunderstanding have confused the ancestors of the O'Odham, Hopi, and Zuni people with the name Hohokam, which is not a word in any of their languages nor the name of a separate people."
- 1100 West Ruins Drive in Coolidge, Arizona, about 65 miles north of Tucson
