- Flows north from Mexico into Arizona, bridging the Chihuahuan and Sonoran Deserts ... eventually joins the Gila River near Winkelman, Arizona
- Approximately 175 miles in total, with about 140 miles within Arizona.
- One of the last major undammed desert rivers in the American Southwest
- Boasts exceptional biodiversity, supporting a wide range of species from both desert environments and the nearby "Sky Islands" (mountain ranges with unique ecosystems)
- The river's riparian habitat (vegetation along the riverbanks) serves as a critical stopover point for millions of migratory birds each year ... recognized as a globally important bird area
- Home to numerous species of mammals, birds, reptiles, amphibians, and fish, including several endangered and imperiled species
- The San Pedro River Valley has a long history of human occupation, with archaeological sites dating back 13,000 years
- The San Pedro Riparian National Conservation Area (SPRNCA) protects a significant portion of the river and its ecosystem ... various organizations work to raise awareness and protect the river's health
- Groundwater pumping, poorly planned development, and invasive species pose challenges to the river's water flow and habitat ... 2022: the San Pedro River was listed as one of America's Most Endangered Rivers
- Settlements near the river include Benson, Sierra Vista, Bisbee, Tombstone, and Oracle
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